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Quantity: 100 ul                                                                                 Application: WB

Predicted I Observed M.W.: 59 kDa                                                    Uniprot ID: O75030

Background:

Microphthalmia-associated transcription factor (MITF) belongs to the MiT/TFE family. MITF is a transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. MITF binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). 

Other Names:

Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, bHLHe32, BHLHE32

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human MITF. Antibodies were purified by affinity purification using immunogen.

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: