Abiocode Logo

Quantity: 100 ul                                                                                          Application: WB

Predicted I Observed M.W.: 62 kDa                                                            Uniprot ID: P98077

Background:

SHC-transforming protein 2 (SHC2) is a signaling adapter protein that contains a PID domain and an SH2 domain. SHC2 couples activated growth factor receptors to signaling pathway in neurons. SHC2 interacts with the Trk receptors in a phosphotyrosine-dependent manner, and is involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.  SHC2 is highly expressed in brain, although it is also expressed in other cell types, such as endothelial cells .

Other Names:

SHC-transforming protein 2, Protein Sck, SHC-transforming protein B, Src homology 2 domain-containing-transforming protein C2, SH2 domain protein C2, SCK, SHCB, SLI

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human SHC2. Antibodies were purified by affinity purification using immunogen.

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: