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Application: WB, IP, ChIP                                                                       Quantity: 100 ul

Predicted I Observed M.W.: 102 I 120 kDa                                               Uniprot ID: Q9Y6K1

Background:

DNA (cytosine-5)-methyltransferase 3A (DNMT3A) is required for genome wide de novo methylation and is integral for the formation of DNA methylation patterns during development.  DNA methylation is coordinated with methylation of histones.  DNMT3A modifies DNA in a non-processive manner and is involved in the methylation of CpG island as well as non-CpG island. 

Other Names:

DNMT3A2, DNA MTase HsaIIIA, M.HsaIIIA

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human DNMT3A. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

IP & ChIP: 1:100-1:200

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: