Products

R2064-vp - PDS5A (vPairTM) Antibodies

Catalog No. R2064-vp
Product Name PDS5A (vPairTM) Antibodies
Price $299
  
 

Predicted I Observed M.W.: 151 kDa                                                          Uniprot ID: Q6A026

Application: WB

Quantity:        50 ul PDS5A (C1) (R2064-1) Rabbit Polyclonal Antibody

                      50 ul PDS5A (C3) (R2064-3) Rabbit Polyclonal Antibody 


Product Introduction:

vPairTM antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Abiocode to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody-based assays. The use of a pair of fully characterized vPairTM antibodies in the same assay can validate signal specificity since vPairTM antibodies recognize two independent epitopes of the same protein. Different sets of vPairTM antibodies are developed at Abiocode to work with specific applications, including antibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS.

Background:

Sister chromatid cohesion protein PDS5 homolog A (PDS5A) belongs to the PDS5 family and is a probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. PDS5A may couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.

Other Names:

Sister chromatid cohesion protein PDS5 homolog A, Cell proliferation-inducing gene 54 protein, Sister chromatid cohesion protein 112, SCC-112, PIG54

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing 2 distinct C-terminal regions of either human [PDS5A (C1) (R2064-1)] or mouse [PDS5A (C3) (R2064-3)] PDS5A. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data:

PDS5A Antibody Western (Abiocode)

Fig 1.  Western blot of total cell extracts from
A) human HeLa, B) human Jurkat, C) mouse
thymus; using 2 independent Abs against 2 distinct
regions of human or mouse PDS5A at RT for 2 h.