R1278-1 - WNK4 (N) Antibody, Rabbit Polyclonal

Catalog No. R1278-1
Product Name WNK4 (N) Antibody, Rabbit Polyclonal
Price $249

Quantity: 100 ul                                                                                          Application: WB

Predicted I Observed M.W.: 135 kDa                                                          Uniprot ID: Q96J92


Serine/threonine-protein kinase WNK4 belongs to the Ser/Thr protein kinase family. It is a serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. WNK4 acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Mutations in WNK4 can lead to pseudohypoaldosteronism 2B.

Other Names:

Serine/threonine-protein kinase WNK4, Protein kinase lysine-deficient 4, Protein kinase with no lysine 4, PRKWNK4

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human WNK4. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data:

WNK4 Antibody Western (Abiocode)

Fig 1.  Western blot of total cell extracts
from A) mouse thymus; B) human HeLa;
C) human Jurkat; using anti-WNK4 (N)
(R1278-1) at RT for 2 h.