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R2677-1 - YAF2 (M) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 20 kDa Uniprot ID: Q8IY57 Background: YY1-associated factor 2 (YAF2) is a nuclear protein that contains a RanBP2-type zinc finger. YAF2 binds to MYC and inhibits MYC-mediated transactivation. YAF2 also binds to MYCN and enhances MYCN-dependent transcriptional activation. YAF2 interacts with YY1 and increases calpain 2-mediated proteolysis of YY1 in vitro. YAF2 is also a component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling. Other Names: YY1-associated factor 2 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing middle region of human YAF2. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts from(A) human HeLa, (B) human Jurkat; using anti-YAF2 (M) (R2677-1) at RT for 2 h. |