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Quantity: 100 ul                                                                                             Application: WB

Predicted | Observed MW: 39 | 46 kDa                                                       Uniprot ID: O15527

Background:

N-glycosylase/DNA lyase (OGG1) belongs to the type-1 OGG1 family and is a DNA repair enzyme that incises DNA at 8-oxoG residues. OGG1 excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. OGG1 has a beta-lyase activity that nicks DNA 3' to the lesion.

Other Names:

N-glycosylase/DNA lyase, MMH, MUTM, OGH1

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human OGG1. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications: 

WB: 1:500-1:2,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: