Products

R0829-vp - AXIN2 (vPairTM) Antibodies

Catalog No. R0829-vp
Product Name AXIN2 (vPairTM) Antibodies
Price $249
  
 

Predicted M.W.: 94 kDa                                                                    Uniprot ID: Q9Y2T1

Application: WB

Quantity:        50 ul AXIN2 (C1) (R0829-2) Rabbit Polyclonal Antibody &

                        50 ul AXIN2 (C2) (R0829-3) Rabbit Polyclonal Antibody


Product Introduction:

vPairTM antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Abiocode to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody-based assays. The use of a pair of fully characterized vPairTM antibodies in the same assay can validate signal specificity since vPairTM antibodies recognize two independent epitopes of the same protein. Different sets of vPairTM antibodies are developed at Abiocode to work with specific applications, including antibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS.

Background:

Axin-2 (AXIN2) may act as an inhibitor of the Wnt signaling pathway by down-regulating beta-catenin. The deregulation of beta-catenin has been implicated as an important event in the development of a number of malignancies. Defects in AXIN2 are involved in colorectal cancer (CRC) and oligodontia-colorectal cancer syndrome (ODCRCS).

Other Names:

Axin-2, Axin-like protein, Axil, Axis inhibition protein 2, Conductin

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing two distinct C-terminal regions [AXIN2 (C1) (R0829-2); AXIN2 (C2) (R0829-3)] of human AXIN2. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications: 

WB: 1:500-1:1,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data:

AXIN2 Antibody Western (Abiocode)

Fig 1. Western blot of total cell extracts from human
Jurkat, using 2 independent antibodies against two
distinct C-terminal regions of human AXIN2 (A: R0829-2;
B: R0829-3) at RT for 2 h.