R3010-1 - HEY2 (C) Antibody, Rabbit Polyclonal

Catalog No. R3010-1
Product Name HEY2 (C) Antibody, Rabbit Polyclonal
Price $249

Quantity: 100 ul                                                                               Application: WB

Predicted I Observed M.W.: 36 I 45 kDa                                            Uniprot ID: Q9UBP5


Hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2) belongs to the HEY family and is a downstream effector of Notch signaling which may be required for cardiovascular development. HEY2 is a transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. HEY2 also represses transcription by the cardiac transcriptional activators GATA4 and GATA6.

Other Names:

Hairy/enhancer-of-split related with YRPW motif protein 2, Cardiovascular helix-loop-helix factor 1, hCHF1, Class B basic helix-loop-helix protein 32, bHLHb32, HES-related repressor protein 2, Hairy and enhancer of split-related protein 2, HESR-2, Hairy-related transcription factor 2, HRT-2, hHRT2, Protein gridlock homolog, HLHB32, CHF1, GRL, HERP, HERP1, HRT2

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human HEY2. Antibodies were purified by affinity purification using immunogen.

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data:

HEY2 Antibody Western (Abiocode)

Fig 1.  Western blot of total cell extracts from
A) mouse brain, B) mouse thymus, C) human
HeLa, D) human Jurkat; using anti-HEY2 (C1)
(R3010-1) at RT for 2 h.