R0147-1 - FANCI (C1) Antibody, Rabbit Polyclonal

Catalog No. R0147-1
Product Name FANCI (C1) Antibody, Rabbit Polyclonal
Price $219

Quantity: 100 ul                                                                                 Application: WB

Predicted M.W.: 149 kDa                                                                   Uniprot ID: Q9NVI1


Fanconi anemia, complementation group I (FANCI) is required for maintenance of chromosomal stability.  It plays a role in the repair of DNA double-strand breaks by homologous recombination and in the repair of DNA crosslinks.  In response to DNA damage it is involved in the S phase and G2 phase checkpoints of the cell cycle.  FANCI also promotes FANCD2 ubiquitination and recruitment to DNA repair sites.  Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage and defective DNA repair.  

Other Names:

FLJ10719, KIAA1794, Protein FACI

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region (distinct from the C-terminal region for R0147-2) of human FANCI.  Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:


Tested Applications: 

WB: 1:1,000-1:5,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data:

FANCI Antibody Western (Abiocode)

Fig 1. Western blot of total cell extracts
from human HeLa, using Ab (A) R0147-1;
(B) R0147-2; or (C) R0147-3 at RT for 2 h.