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R0721-2 - GATA2 (C1) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted | Observed MW: 51 kDa Uniprot ID: P23769 Background: Endothelial transcription factor GATA-2 is a transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. GATA2 binds to the consensus sequence 5'-AGATAG-3'. Defects in GATA2 are the cause of dendritic cell monocyte lymphocyte B and natural killer lymphocyte deficiency (DCML), of lymphedema primary with myelodysplasia (LMPM), and of myelodysplastic syndrome (MDS). Other Names: Endothelial transcription factor GATA-2, GATA-binding protein 2 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human GATA2. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extractsfrom human HeLa; using anti-GATA2 (C1) (R0721-2) at RT for 2 h. |