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R3161-1 - SEH1L (N) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 40 kDa Uniprot ID: Q96EE3 Background: Nucleoporin SEH1 (SEH1L) is a component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. SEH1L plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. As a component of the GATOR2 complex, SEH1L inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway. Other Names: Nucleoporin SEH1, Nup107-160 subcomplex subunit SEH1, SEC13-like protein, SEC13L, SEH1 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human SEH1L. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts frommouse thymus; using anti-SEH1L (N) (R3161-1) at RT for 2 h. |