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Quantity: 100 ul                                                                                          Application: WB

Predicted I Observed M.W.: 83 I 100 kDa                                                   Uniprot ID: Q9UPW6

Background:

DNA-binding protein SATB2 belongs to the CUT homeobox family. SATB2 binds to DNA, at nuclear matrix- or scaffold-associated regions. Furthermore, SATB2 is thought to recognize the sugar-phosphate structure of double-stranded DNA. SATB2 is a transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Also, SATB2 acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers.

Other Names:

DNA-binding protein SATB2, Special AT-rich sequence-binding protein 2

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human SATB2. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: