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Quantity: 100 ul                                                                                        Application: WB

Predicted I Observed M.W.: 135 I 150-160 kDa                                         Uniprot ID: Q9BXA9

Background:

Sal-like protein 3 (SALL3) is a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. SALL3 binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of SALL3, resulting in acceleration of DNA methylation, may have a role in oncogenesis [provided by RefSeq].

Other Names:

Sal-like protein 3, Zinc finger protein 796, Zinc finger protein SALL3, hSALL3, ZNF796

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human SALL3. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: